|
学术问题就不谈了,下面2017年的文章大家都懂的。
简单说,mRNA剂量低了没效果,剂量高了太毒, 人体受不了。 Modern搞了十年,什么药都做不下去了,发现疫苗正合适, 只要两针, 毒性低。
But the Crigler-Najjar treatment has been indefinitely delayed, an Alexion spokeswoman told STAT. It never proved safe enough to test in humans, according to several former Moderna employees and collaborators who worked closely on the project. Unable to press forward with that technology, Moderna has had to focus instead on developing a handful of vaccines, turning to a less lucrative field that might not justify the company’s nearly $5 billion valuation.
“It’s all vaccines right now, and vaccines are a loss-leader,” said one former Moderna manager. “Moderna right now is a multibillion-dollar vaccines company, and I don’t see how that holds up.”
赶上新冠,Moderna终于出了第一款产品。
两针看来很安全。问题是要不要打第三针对付变种;将来要不要每年, 每半年都打。要打的话,毒性问题会不会又来了。 |
|