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发表于 2021-4-26 10:21 AM
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Synaptogenix to Present at Sachs 4th Annual Neuroscience Innovation Forum
PR Newswire
NEW YORK, April 26, 2021
NEW YORK, April 26, 2021 /PRNewswire/ -- Synaptogenix, Inc. (OTC: SNPX) ("Synaptogenix" or the "Company"), an emerging biopharmaceutical company focused on developing therapies for neurodegenerative diseases, today announced that Dr. Daniel Alkon, the Company's President and Chief Scientific Officer, will present a "Spotlight Showcase" of Synaptogenix under the title "Regenerative Therapeutics" on Wednesday, April 28th at 12:40pm ET.
"Synaptogenix's regenerative therapeutics for neurodegeneration is based on extensive pre-clinical data demonstrating the induction of new, fully mature synaptic connections that restore cognitive function in models of Alzheimer's disease ("AD"), stroke, Fragile X syndrome, mental retardation and traumatic brain injury. Synaptogenix's lead compound, Bryostatin-1, working through natural pathways in the brain, appears to activate a repertoire of synaptic growth factors including BDNF, NGF, HGF, and IGF to 'rewire' the degenerating brain. Rewiring of synaptic networks could explain the recent signals of clinical benefits demonstrating significant, persistent improvement of the Severe Impairment Battery (SIB) – over baseline – shown for advanced AD patients in the Company's clinical trials. Regenerative efficacy of bryostatin, and other Synaptogenix platform drugs, is complemented by other demonstrated efficacies to prevent neuronal death, reduce A Beta-oligomers, and reduce tau phosphorylation in pre-clinical AD models. A six-month, National Institutes of Health-supported clinical trial with Bryostatin-1 is ongoing. Clinical trials for other indications such as Fragile X syndrome and multiple sclerosis are also being considered," stated Dr. Alkon.
The Company's presentation will be available on demand during the conference to registered participants through Sachs Forum website. It will also be accessible via social media one week after the meeting. To register in advance, please visit www.sachsforum.com. Dr. Daniel Alkon will also be available for 1x1 meetings during the forum between April 26th and April 30th.
About Synaptogenix, Inc.
Synaptogenix is a clinical-stage biopharmaceutical company that has historically worked to develop novel therapies for neurodegenerative diseases. Synaptogenix has conducted clinical and preclinical studies of its lead therapeutic candidate, Bryostatin-1, in AD. Preclinical studies have also demonstrated bryostatin's regenerative mechanisms of action for the rare disease, Fragile X syndrome, and for other neurodegenerative disorders such as multiple sclerosis, stroke, and traumatic brain injury. The U.S. Food and Drug Administration has granted Orphan Drug Designation to Synaptogenix for Bryostatin-1 as a treatment for Fragile X syndrome. Bryostatin-1 has already undergone testing in more than 1,600 people in cancer studies, thus creating a large safety data base that will further inform clinical trial designs.
Additional information about Synaptogenix, Inc. may be found on its website: www.synaptogen.com.
更多细节 Sacks Forum: https://www.sachsforum.com/4nif-about.html
Agenda: https://www.sachsforum.com/uploa ... if_draft_agenda.pdf
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